Synthetic Chemistry

What is synthetic chemistry but a collaboration between Ricerca’s synthetic chemists and engineers enabling the successful production of your product. This chemistry process is a hallmark of Ricerca’s highly successful synthetic chemistry services and synthetic process chemistry services. Our synthetic chemists and engineers communicate freely with each other and with you throughout the entire process, ensuring safe, fast, and economical synthetic chemical, synthetic processing, and chemistry scale up projects. Our broad range of small molecule expertise includes diverse chemistries on both chiral and achiral molecules. We are also able to combine novel and established chemistry synthetic technologies.

Ricerca’s synthetic chemistry services include:

  • Process research
  • De novo synthesis
  • Radiochemistry synthesis (non–GMP and cGMP)
  • Stable labeling synthesis
  • Impurity and analog identification and synthesis
  • Synthesis of analytical reference standards
  • Route evaluation & selection
  • Process optimization
  • Robustness and process limits testing
  • Process justification
  • Preparation of cGMP-grade API for preclinical and clinical needs


Synthetic Chemistry — Tools & Capabilities

  • Process Research Laboratories
  • – General purpose — mg to kg
    – Processing scale — up to 12 liters
    – Pressure range: FV to 50 psig
    – Temperature range: –78 to +200 C

  • Radiochemistry Labs (cGMP & non-cGMP)
  • – Licensed for 3H, 14C, 32P, 35S, 131l, 125l, 99Tc, 36Cl

  • cGMP Kilo Labs
  • – HEPA — filtered air system
    – Processing scale to 50 liters
    – Temperature range: –78 to +200 C
    – Dedicated single process use

  • General Purpose Kilo Labs
  • – Processing scale to 50 liters
    – Temperature range: –78 to +200 C
    – Large scale chromotography capable